Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 10/20 | 0.44 |
| ▸ | TUBB | P07437 | 10/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835279 | 0.86 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4035604 | 0.85 | ACHE (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4043016 | 0.85 | ROCK2 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4035517 | 0.82 | TYMS (0.37) | POLBEPHX1TYMSLMNAHPGD | |
| SCHEMBL2349768 | 0.81 | POLB (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1827677 | 0.81 | POLB (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3269989 | 0.81 | KDR (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL24074239 | 0.78 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3270806 | 0.77 | TYMS (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4036741 | 0.76 | RAF1 (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791537-B1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2009-10-14 | — | — | EP | claimed |