7-Acetoxycoumarin

7-Acetoxycoumarin

SCHEMBL1827872

CC(=O)Oc1ccc2ccc(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 1.00
CA12 O43570 6/20 1.00
CA9 Q16790 6/20 1.00
GLA P06280 6/20 1.00
GAA P10253 5/20 1.00
POLB P06746 2/20 1.00
TDP1 Q9NUW8 1/20 1.00
KMT2A Q03164 9/20 0.65
GBA1 P04062 2/20 0.65
ALDH1A1 P00352 7/20 0.65
HSD17B10 Q99714 3/20 0.65
CA1 P00915 2/20 0.65
HPGD P15428 2/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
CA5A P35218 2/20 0.65
CA7 P43166 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CA3 P07451 1/20 0.65
AKR1B1 P15121 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16283612 0.89 CA12 (1.00) KDM4ECA12CA9GLAGAA
SCHEMBL19900130 0.86 KDM4E (0.75) KDM4ECA12CA9GLAGAA
SCHEMBL557165 0.84 CA12 (0.73) KDM4ECA12CA9GLAGAA
SCHEMBL7719122 0.84 KDM4E (0.73) KDM4ECA12CA9GLAGAA
SCHEMBL8425143 0.84 KDM4E (0.72) KDM4ECA12CA9GLAGAA
SCHEMBL24017162 0.83 KDM4E (0.71) KDM4ECA12CA9GLAGAA
SCHEMBL14329565 0.83 CA12 (0.71) KDM4ECA12CA9GLAGAA
SCHEMBL14473955 0.83 KDM4E (0.70) KDM4ECA12CA9GLAGAA
SCHEMBL22579707 0.83 KDM4E (0.70) KDM4ECA12CA9GLAGAA
SCHEMBL31190256 0.83 CA12 (0.70) KDM4ECA12CA9GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574109-A Preparation method and application of 8-hydroxy psoralen 河南中烟工业有限责任公司 2023-08-11 CN claimed
CN-116554192-A Synthesis method of 8-methoxy psoralen 河南中烟工业有限责任公司 2023-08-08 CN claimed
CN-105885831-B Thiosemicarbazides contracting umbelliferone -8- aldehyde probe reagent and its preparation and application 贵州大学 2018-12-28 CN claimed
CN-106008435-A Fluorescence-enhanced fluorescent probe for detection of Au<3+> and preparation method thereof 华南理工大学 2016-10-12 CN claimed
EP-2001463-B1 A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS COUNCIL SCIENT IND RES (IN) 2013-07-03 EP claimed
US-20120277297-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2012-11-01 US claimed
US-8188143-B2 Pharmaceutical composition useful as acetylcholinesterase inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2012-05-29 US claimed
EP-2229715-A2 SEMICONDUCTOR LASER HAVING ABSORPTION LAYER Technische Universität Wien (AT) 2010-09-22 EP claimed
WO-2009070821-A2 SEMICONDUCTOR LASER HAVING ABSORPTION LAYER TECHNISCHE UNIVERSITÄT WIEN (AT) 2009-06-11 WO claimed
EP-2001463-A1 A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS Council of Scientific and Industrial Research (IN) 2008-12-17 EP claimed
US-20080009544-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-01-10 US claimed
WO-2007107846-A1 A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-09-27 WO claimed
US-5512667-A Trifunctional intermediates for preparing 3'-tailed oligonucleotides DRUG ROYALTY LP1 (CA) 1996-04-30 US claimed
EP-0403535-A1 COUMARINS TO INHIBIT REVERSE TRANSCRIPTASE IN HUMANS THE UPJOHN COMPANY (US) 1990-12-27 EP claimed
WO-1989007939-A2 COUMARINS TO INHIBIT REVERSE TRANSCRIPTASE IN HUMANS THE UPJOHN COMPANY (US) 1989-09-08 WO claimed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
WO-1989007939-A2 COUMARINS TO INHIBIT REVERSE TRANSCRIPTASE IN HUMANS THE UPJOHN COMPANY (US) 1989-09-08 WO disclosed
WO-1989007939-A2 COUMARINS TO INHIBIT REVERSE TRANSCRIPTASE IN HUMANS THE UPJOHN COMPANY (US) 1989-09-08 WO disclosed
US-4104368-A STEARYLDIMETHYLBENZYLAMMONIUM P-AMINOBENZOATE MILLMASTER ONYX CORPORATION (US) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009544-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors ACHE, BCHE, CHRNB1 KDM4E 1482/4885CA12 815/4885CA9 1675/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 KDM4E 1365/4885CA12 696/4885CA9 512/4885
US-20120277297-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors ACHE, BCHE, CYP3A7 KDM4E 1461/4885CA12 1536/4885CA9 1968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.