Propene

Propene

SCHEMBL18280342

C=CC.CCOP(=O)(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.44
TSHR P16473 2/20 0.43
PPARD Q03181 2/20 0.43
LPAR2 Q9HBW0 6/20 0.42
LPAR1 Q92633 4/20 0.41
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL17060515 0.87 TSHR (0.50) LPAR3TSHRPPARDLPAR2LPAR1
Ethylene SCHEMBL790436 0.87
SCHEMBL40792 0.87
SCHEMBL27666183 0.87 TSHR (0.56) LPAR3TSHRPPARDLPAR2LPAR1
Acrylic Acid SCHEMBL21436574 0.84 LMNA (0.43) LPAR3TSHRPPARDLPAR2LPAR1
SCHEMBL2470581 0.84
SCHEMBL20543353 0.84
Ammonia Solution, Strong SCHEMBL4429272 0.84
Hydrochloric Acid SCHEMBL10348676 0.84
SCHEMBL3218090 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303415-B1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF ALCON INC (CH) 2022-12-28 EP disclosed
EP-3383854-B1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF ALCON INC (CH) 2021-03-03 EP disclosed
US-10823983-B2 UV-absorbing vinylic monomers and uses thereof ALCON INC. (CH) 2020-11-03 US disclosed
US-10472319-B2 Water-soluble UV-absorbing compounds and uses thereof NOVARTIS AG (CH) 2019-11-12 US disclosed
US-20190256455-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF ALCON INC. (CH) 2019-08-22 US disclosed
US-10324311-B2 Visible-light photoinitiators and uses thereof NOVARTIS AG (CH) 2019-06-18 US disclosed
US-10322993-B2 Water-soluble UV-absorbing compounds and uses thereof NOVARTIS AG (CH) 2019-06-18 US disclosed
US-20190179170-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2019-06-13 US disclosed
US-10254567-B2 UV-absorbing vinylic monomers and uses thereof NOVARTIS AG (CH) 2019-04-09 US disclosed
EP-3419966-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF Novartis AG (CH) 2019-01-02 EP disclosed
EP-3383854-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF Novartis AG (CH) 2018-10-10 EP disclosed
EP-3303415-A1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF Novartis AG (CH) 2018-04-11 EP disclosed
WO-2017145024-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF NOVARTIS AG (CH) 2017-08-31 WO disclosed
US-20170242275-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF ALCON INC. (CH) 2017-08-24 US disclosed
WO-2017093835-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2017-06-08 WO disclosed
US-20170158611-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF ALCON INC. (CH) 2017-06-08 US disclosed
US-20160357031-A1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF ALCON INC. (CH) 2016-12-08 US disclosed
WO-2016193912-A1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF NOVARTIS AG (CH) 2016-12-08 WO disclosed
CN-1317790-C Nonaqueous electrolyte and secondary lithium battery using the same MITSUBISHI CHEM CORP (JP) 2007-05-23 CN disclosed
CN-1411619-A Nonaqueous electrolyte and secondary lithium battery using the same MITSUBISHI CHEM CORP (JP) 2003-04-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158611-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF CRYZ, UACA, XRCC5 LPAR3 4390/4885TSHR 3980/4885PPARD 414/4885
US-20170242275-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF UACA, VCL, CRYZ LPAR3 4824/4885TSHR 3951/4885PPARD 599/4885
US-10324311-B2 Visible-light photoinitiators and uses thereof SIRT5, IK, IGLV6-57 LPAR3 2366/4885TSHR 3033/4885PPARD 161/4885
US-10823983-B2 UV-absorbing vinylic monomers and uses thereof UACA, VCL, CRYZ LPAR3 4824/4885TSHR 3951/4885PPARD 599/4885
US-20190179170-A1 UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF UACA, VCL, CRYZ LPAR3 4824/4885TSHR 3951/4885PPARD 599/4885
US-20160357031-A1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF SIRT5, IK, IGLV6-57 LPAR3 2366/4885TSHR 3033/4885PPARD 161/4885
US-10254567-B2 UV-absorbing vinylic monomers and uses thereof UACA, VCL, CRYZ LPAR3 4824/4885TSHR 3951/4885PPARD 599/4885
US-10472319-B2 Water-soluble UV-absorbing compounds and uses thereof CRYZ, UACA, XRCC5 LPAR3 4390/4885TSHR 3980/4885PPARD 414/4885
US-10322993-B2 Water-soluble UV-absorbing compounds and uses thereof CRYZ, UACA, XRCC5 LPAR3 4390/4885TSHR 3980/4885PPARD 414/4885
US-20190256455-A1 WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF CRYZ, UACA, XRCC5 LPAR3 4390/4885TSHR 3980/4885PPARD 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.