Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802810 | 0.86 | HTR2C (0.47) | MAPTMAOAKDM4EALDH1A1GAA | |
| SCHEMBL23183201 | 0.74 | MPO (0.41) | CHRNA7 | |
| SCHEMBL20896943 | 0.74 | MPO (0.45) | MAPTMAOAKDM4EALDH1A1CHRNA7 | |
| SCHEMBL31022888 | 0.73 | CHRNB2 (0.35) | — | |
| SCHEMBL9404868 | 0.72 | KDM4E (0.50) | MAPTCYP3A4MAOAKDM4EALDH1A1 | |
| SCHEMBL5115297 | 0.69 | MAPT (0.45) | MAPTCYP3A4MAOAKDM4EALDH1A1 | |
| SCHEMBL2594537 | 0.69 | MAPT (0.68) | MAPTCYP3A4MAOAKDM4EALDH1A1 | |
| SCHEMBL14481557 | 0.69 | MAPT (0.68) | MAPTCYP3A4MAOAKDM4EALDH1A1 | |
| SCHEMBL29924708 | 0.69 | MAPT (0.68) | MAPTCYP3A4MAOAKDM4EALDH1A1 | |
| SCHEMBL8543417 | 0.69 | MAOA (0.55) | MAPTCYP3A4MAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315614-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010022995-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2010-03-04 | — | — | WO | disclosed |