Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950964 | 0.82 | HTT (0.35) | KMT2AARG1 | |
| SCHEMBL951739 | 0.82 | HTT (0.35) | KMT2AARG1 | |
| SCHEMBL5694169 | 0.70 | HTT (0.31) | — | |
| Gamma-Aminobutyric Acid SCHEMBL190459 | 0.66 | LMNA (1.00) | LMNATHRBBLMKMT2ANPSR1 | |
| Gamma-Aminobutyric Acid SCHEMBL1330421 | 0.66 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL3973563 | 0.66 | LMNA (1.00) | LMNATHRBBLMKMT2ANPSR1 | |
| Gamma-Aminobutyric Acid SCHEMBL4878 | 0.66 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL4357842 | 0.65 | TSHR (0.75) | LMNATHRBBLMKMT2ANPSR1 | |
| SCHEMBL6290400 | 0.65 | ARG1 (0.38) | KMT2AARG1 | |
| Gamma-Aminobutyric Acid SCHEMBL5181606 | 0.65 | TSHR (0.83) | LMNATHRBBLMKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318433-A2 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010016944-A2 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2010-02-11 | — | — | WO | disclosed |