Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190446 | 1.00 | HTT (0.35) | HTTAPLNRARG1KMT2A | |
| SCHEMBL950964 | 1.00 | HTT (0.35) | HTTAPLNRARG1KMT2A | |
| Allylamine SCHEMBL27651104 | 0.85 | ARG1 (0.30) | ARG1 | |
| Allylamine SCHEMBL27651106 | 0.85 | ARG1 (0.30) | ARG1 | |
| SCHEMBL13534665 | 0.84 | — | — | |
| Valine SCHEMBL16004731 | 0.83 | SLC7A5 (0.46) | — | |
| Gamma-Aminobutyric Acid SCHEMBL1828323 | 0.82 | LMNA (0.44) | ARG1KMT2A | |
| SCHEMBL5694169 | 0.81 | HTT (0.31) | HTT | |
| SCHEMBL1770442 | 0.79 | ARG1 (0.38) | HTTAPLNRARG1KMT2A | |
| SCHEMBL6290400 | 0.79 | ARG1 (0.38) | HTTAPLNRARG1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346026-B1 | MICROORGANISM PRODUCING 5'-INOSINIC ACID AND PROCESS FOR PRODUCING 5'-INOSINIC ACID USING THE SAME | CJ CHEILJEDANG CORP (KR) | 2009-04-01 | — | — | EP | claimed |
| CN-1406273-A | Microorganism producing 5'-inosinic acid and process for producing 5'-inosinic acid using the same | CHEIL JEDANG CORP (KR) | 2003-03-26 | — | — | CN | claimed |
| EP-3061828-B1 | METHOD FOR PRODUCING TARGET SUBSTANCE | AJINOMOTO KK (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-11965198-B2 | Method for producing target substance by bacterial fermentation | AJINOMOTO CO., INC. (JP) | 2024-04-23 | — | — | US | disclosed |
| CN-117802187-A | Process for producing purine compounds | 味之素株式会社 | 2024-04-02 | — | — | CN | disclosed |
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| EP-3861109-A1 | METHOD FOR PRODUCING TARGET SUBSTANCE BY BACTERIAL FERMENTATION | AJINOMOTO CO., INC. (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-11066416-B2 | Rapafucin derivative compounds and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-07-20 | — | — | US | disclosed |
| WO-2021067439-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-04-08 | — | — | WO | disclosed |
| US-20210094933-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2021-04-01 | — | — | US | disclosed |
| WO-2020071538-A1 | METHOD FOR PRODUCING TARGET SUBSTANCE BY BACTERIAL FERMENTATION | AJINOMOTO CO., INC. (JP) | 2020-04-09 | — | — | WO | disclosed |
| CN-1406273-A | Microorganism producing 5'-inosinic acid and process for producing 5'-inosinic acid using the same | CHEIL JEDANG CORP (KR) | 2003-03-26 | — | — | CN | disclosed |
| US-20030032150-A1 | Process for producing optically active (4r)-1,3-tiazolidine-4-carboxylic acid | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2003-02-13 | — | — | US | disclosed |
| US-6211212-B1 | DRUGS WITH AMIDE AND ESTER GROUPS AS ENZYME INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-04-03 | — | — | US | disclosed |
| US-6022885-A | Pyrrolidine and thiazole derivatives with antibacterial and . metallo-.beta-lactamase inhibitory properties | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-02-08 | — | — | US | disclosed |
| EP-0970062-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998040056-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1998-09-17 | — | — | WO | disclosed |
| US-4775675-A | Thiazolidinecarboxylic acid derivatives and treatment of liver diseases therewith | BIOGAL GYOGYSZERGYAR (HU) | 1988-10-04 | — | — | US | disclosed |
| CN-86104085-A | The preparation method of Thiazolidinecarboxylacid acid derivatives | — | 1987-04-22 | — | — | CN | disclosed |
| EP-0206197-A1 | 5,5-Dimethyl-thiazolidin-4(S)-carboxylic-acid derivatives, method for their preparation and medicines containing them | BIOGAL GYOGYSZERGYAR (HU) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066416-B2 | Rapafucin derivative compounds and methods of use thereof | RICTOR, FKBP14, MTOR | HTT 2094/4885APLNR 1226/4885ARG1 2742/4885 |
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RICTOR, FKBP14, MTOR | HTT 2094/4885APLNR 1226/4885ARG1 2742/4885 |
| US-20210094933-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RICTOR, FKBP14, MTOR | HTT 2094/4885APLNR 1226/4885ARG1 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.