Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808506 | 1.00 | KDR (0.36) | KDRMAPK14TNNI3KMAPTL3MBTL1 | |
| SCHEMBL24786607 | 0.84 | SCN9A (0.36) | KDRMAPK14TNNI3KALDH1A1 | |
| SCHEMBL18284583 | 0.81 | HTR2A (0.38) | MAPTL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL23370326 | 0.73 | ADORA2A (0.35) | KDRMAPK14TNNI3KALDH1A1 | |
| SCHEMBL29551489 | 0.73 | L3MBTL1 (0.39) | L3MBTL1CYP1A2CYP2C19HSP90AA1HSP90AB1 | |
| SCHEMBL22691166 | 0.73 | L3MBTL1 (0.39) | L3MBTL1CYP1A2CYP2C19HSP90AA1HSP90AB1 | |
| SCHEMBL23370441 | 0.71 | NPC1 (0.35) | KDRMAPK14TNNI3KL3MBTL1NPC1 | |
| SCHEMBL12825945 | 0.70 | KEAP1 (0.51) | KDRMAPK14TNNI3KMAPTL3MBTL1 | |
| SCHEMBL23370324 | 0.70 | ALDH1A1 (0.34) | KDRMAPK14TNNI3KHPGDALDH1A1 | |
| SCHEMBL12825961 | 0.67 | SMN1; SMN2 (0.55) | MAPTHPGDNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045497-B1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-22 | — | — | EP | disclosed |
| US-20220400676-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-22 | — | — | US | disclosed |
| US-20220400676-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-22 | — | — | US | disclosed |
| WO-2021074325-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220400676-A1 | HERBICIDAL COMPOUNDS | DDT, NQO2, CBR3 | KDR 3551/4885MAPK14 4064/4885TNNI3K 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.