Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107144 | 0.98 | SLC7A5 (0.56) | SLC7A5CTBP2POLBALDH1A1GAA | |
| SCHEMBL12400239 | 0.87 | SLC7A5 (0.68) | SLC7A5ALDH1A1GAAGFERHSP90AB1 | |
| SCHEMBL11553441 | 0.85 | CTBP2 (0.56) | CTBP2POLBALDH1A1L3MBTL1NPC1 | |
| SCHEMBL1107143 | 0.82 | KMT2A (0.56) | CTBP2POLBALDH1A1L3MBTL1NPC1 | |
| SCHEMBL25463180 | 0.82 | CTBP2 (0.53) | CTBP2POLBALDH1A1L3MBTL1NPC1 | |
| SCHEMBL4394735 | 0.81 | SLC7A5 (0.62) | SLC7A5ALDH1A1GAAGFERHSP90AB1 | |
| Toluene SCHEMBL27935015 | 0.81 | KMT2A (0.57) | SLC7A5ALDH1A1HSP90AB1L3MBTL1CYP4F2 | |
| SCHEMBL7642195 | 0.81 | CTBP2 (0.51) | CTBP2POLBALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11553448 | 0.81 | CTBP2 (0.51) | SLC7A5CTBP2POLBALDH1A1L3MBTL1 | |
| SCHEMBL1107166 | 0.81 | SIRT2 (0.52) | ALDH1A1L3MBTL1CYP4F2CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10758522-B2 | Small molecule analogs of the nemo binding peptide | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-01 | — | — | US | disclosed |
| US-20180169078-A1 | Small Molecule Analogs of the Nemo Binding Peptide | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-06-21 | — | — | US | disclosed |
| EP-3302468-A1 | SMALL MOLECULE ANALOGS OF THE NEMO BINDING PEPTIDE | The Scripps Research Institute (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016196117-A1 | SMALL MOLECULE ANALOGS OF THE NEMO BINDING PEPTIDE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758522-B2 | Small molecule analogs of the nemo binding peptide | IKBKG, NFKBIA, NFKB1 | SLC7A5 3485/4885CTBP2 1415/4885POLB 186/4885 |
| US-20180169078-A1 | Small Molecule Analogs of the Nemo Binding Peptide | IKBKG, NFKBIA, NFKB1 | SLC7A5 3485/4885CTBP2 1415/4885POLB 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.