Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 15/20 | 0.65 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.65 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.65 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.65 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.65 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289707 | 0.79 | ACP1 (1.00) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL18289821 | 0.76 | ACP1 (0.71) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL18289819 | 0.76 | ACP1 (0.82) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL18289826 | 0.76 | ACP1 (0.71) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL18289801 | 0.72 | ACP1 (0.78) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL30553310 | 0.70 | NPC1 (0.74) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL9036463 | 0.70 | NPC1 (0.74) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL13949524 | 0.68 | CSNK1D (1.00) | ACP1PTPN7PTPN12PTPN13SSU72 | |
| SCHEMBL18289908 | 0.68 | ALDH1A1 (0.76) | ACP1CSNK1DADORA1DYRK1ANPC1 | |
| SCHEMBL31478529 | 0.68 | CSNK1D (0.66) | ACP1PTPN7PTPN12PTPN13SSU72 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196591-A1 | PROTEIN TYROSINE PHOSPHATASES OR SHP2 INHIBITORS AND USES THEREOF | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2016-12-08 | — | — | WO | disclosed |