SCHEMBL18290230

CC(C)c1cc2c(cc1O)[C@@]1(C)CCC[C@](C)(CO)C1[C@H]1Oc3c(C(C)C)cc4c(c3[C@@H]21)C1=CCC[C@](C)(CO)[C@]1(C)C=C4

nearest known ligand 0.41

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	SOD1	P00441	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18290218	0.69	SOD1 (0.40)	SOD1
SCHEMBL18290219	0.68	SOD1 (0.39)	SOD1
SCHEMBL18290211	0.61	SOD1 (0.53)	SOD1
SCHEMBL18290208	0.59	SOD1 (1.00)	SOD1
SCHEMBL18290292	0.59	SOD1 (1.00)	SOD1
SCHEMBL18290229	0.58	SOD1 (0.72)	SOD1
SCHEMBL18290302	0.56	SOD1 (0.47)	SOD1
18-Hydroxyferruginol SCHEMBL18290210	0.56	KARS1 (0.67)	SOD1
18-Hydroxyferruginol SCHEMBL32666150	0.56	KARS1 (0.67)	SOD1
SCHEMBL16006769	0.53	KARS1 (0.43)	SOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016192631-A1	ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME	中国科学院上海药物研究所	2016-12-08	—	—	WO	disclosed