Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26220553 | 0.77 | FERMT2 (0.50) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL29933815 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL624006 | 0.76 | NR4A2 (0.61) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL16010398 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL3854038 | 0.76 | NR4A2 (0.61) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL856135 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL16705392 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL4619603 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4CDK8CCNC | |
| SCHEMBL5767634 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4ACVR1CLK4 | |
| SCHEMBL24338479 | 0.73 | FERMT2 (0.50) | FERMT2GAKGRM4ACVR1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196393-A2 | AUTOPHAGY-INHIBITING COMPOUNDS AND USES THEREOF | PRESAGE BIOSCIENCES, INC. (US) | 2016-12-08 | — | — | WO | disclosed |