Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291609 | 0.87 | LTA4H (0.49) | KMT2ALTA4HACKR3 | |
| SCHEMBL20037837 | 0.87 | LTA4H (0.49) | KMT2ALTA4HACKR3 | |
| SCHEMBL18291546 | 0.86 | KMT2A (0.56) | KMT2ALTA4HACKR3 | |
| SCHEMBL18291590 | 0.85 | ALDH1A1 (0.56) | KMT2ALTA4HACKR3 | |
| SCHEMBL20255310 | 0.85 | LTA4H (0.48) | KMT2ALTA4HACKR3 | |
| SCHEMBL18291640 | 0.82 | S1PR5 (0.57) | KMT2ALTA4H | |
| SCHEMBL20037859 | 0.81 | HRH3 (0.54) | KMT2ALTA4HACKR3 | |
| SCHEMBL18291674 | 0.80 | RAB9A (0.54) | KMT2ALTA4HGAA | |
| SCHEMBL20038428 | 0.80 | KMT2A (0.47) | KMT2A | |
| SCHEMBL2636348 | 0.80 | KDM4E (0.60) | LTA4HACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016194831-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 帝人ファーマ株式会社 | 2016-12-08 | — | — | WO | disclosed |