Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20769804 | 0.87 | LMNA (0.59) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL65737 | 0.87 | LMNA (0.59) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL29757088 | 0.87 | LMNA (0.59) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL67237 | 0.87 | LMNA (0.59) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL1715 | 0.87 | LMNA (0.59) | POLBKDM4ALMNAHSD17B10CRHBP | |
| Propionic Acid SCHEMBL544940 | 0.85 | LMNA (0.54) | POLBKDM4ALMNAHSD17B10CRHBP | |
| Hydrochloric Acid SCHEMBL16820451 | 0.85 | LMNA (0.58) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL5598361 | 0.85 | LMNA (0.58) | POLBKDM4ALMNAHSD17B10CRHBP | |
| SCHEMBL9171150 | 0.85 | LMNA (0.58) | POLBKDM4ALMNAHSD17B10CRHBP | |
| Methane SCHEMBL7338694 | 0.85 | LMNA (0.58) | POLBKDM4ALMNAHSD17B10CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102512408-A | Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy | UCL BIOMEDICA PLC | 2012-06-27 | — | — | CN | disclosed |
| CN-101102816-B | Composition containing ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy | UCL BUSINESS PLC (GB) | 2011-12-07 | — | — | CN | disclosed |
| EP-2319581-A1 | Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy | UCL Business PLC (GB) | 2011-05-11 | — | — | EP | disclosed |
| CN-101102816-A | Composition containing ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy | UCL BUSINESS PLC (GB) | 2008-01-09 | — | — | CN | disclosed |