Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 3/20 | 0.65 |
| ▸ | CASP7 | P55210 | 3/20 | 0.65 |
| ▸ | TTK | P33981 | 2/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170980 | 0.79 | ALDH1A1 (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29693577 | 0.79 | ALDH1A1 (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29941507 | 0.79 | ALDH1A1 (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8866586 | 0.75 | TTK (0.73) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8796647 | 0.74 | MEN1 (0.67) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1296328 | 0.73 | TTK (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7946079 | 0.73 | KDR (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8336855 | 0.73 | CDK2 (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9115256 | 0.72 | TTK (0.64) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7810309 | 0.72 | TTK (0.72) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | MAPT 20/4885KMT2A 810/4885MEN1 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.