Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.61 |
| ▸ | RAF1 | P04049 | 5/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.61 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22229877 | 0.88 | TGFBR1 (0.57) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4869167 | 0.85 | NPY5R (0.56) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6223466 | 0.82 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL28403314 | 0.80 | MAPK13 (0.61) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7991915 | 0.78 | TGFBR1 (0.57) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL28825919 | 0.78 | TGFBR1 (0.82) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4552561 | 0.76 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4551941 | 0.76 | MAPK13 (0.78) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL19868997 | 0.76 | TGFBR1 (0.74) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4079452 | 0.76 | TGFBR1 (0.71) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | MAPK14 636/4885MAPK13 715/4885MAPK12 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.