Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548844 | 0.99 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL18293369 | 0.99 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL30548843 | 0.99 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL8845094 | 0.97 | KDM4E (0.55) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL31237841 | 0.86 | KDM4E (0.49) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL3275498 | 0.86 | KDM4E (0.49) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL28118098 | 0.86 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| SCHEMBL4385146 | 0.83 | KDM4E (0.54) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| Palmitic Acid SCHEMBL20339205 | 0.82 | BLM (0.65) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 | |
| Myristic Acid SCHEMBL9508694 | 0.82 | BLM (0.65) | ALDH1A1CHRNA7CHRNB2CHRNA4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448732-A1 | PRODUCTION OF NORNICOTINE ACYL-DERIVATIVES IN A PLANT HOST | Luxembourg Institute of Science and Technology (LU) | 2024-10-23 | — | — | EP | claimed |
| WO-2023111120-A1 | PRODUCTION OF NORNICOTINE ACYL-DERIVATIVES IN A PLANT HOST | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LU) | 2023-06-22 | — | — | WO | claimed |
| EP-4448732-A1 | PRODUCTION OF NORNICOTINE ACYL-DERIVATIVES IN A PLANT HOST | Luxembourg Institute of Science and Technology (LU) | 2024-10-23 | — | — | EP | disclosed |
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| CN-113917044-B | Method for quantitatively preparing 11 kinds of amide alkaloids in tobacco leaves by gas chromatography-tandem mass spectrometry | 云南省烟草农业科学研究院 | 2023-10-20 | — | — | CN | disclosed |
| WO-2023111120-A1 | PRODUCTION OF NORNICOTINE ACYL-DERIVATIVES IN A PLANT HOST | LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LU) | 2023-06-22 | — | — | WO | disclosed |
| US-20230152284-A1 | METHOD OF QUANTITATIVELY ANALYZING 11 AMIDE ALKALOIDS IN TOBACCO LEAVES USING GAS CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY | YUNNAN ACADEMY OF TOBACCO AGRICULTURAL SCIENCES (CN) | 2023-05-18 | — | — | US | disclosed |
| CN-115927297-A | Primer, recombinant expression vector, transformant, kit, method and application for improving NacNNs content | 云南省烟草农业科学研究院 | 2023-04-07 | — | — | CN | disclosed |
| EP-3972584-A1 | NANOEMULSION COMPOSITIONS COMPRISING BIOLOGICALLY ACTIVE INGREDIENTS | Poviva Corp. (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20160353795-A1 | ACYL NORNICOTINES REDUCE SENSORY IRRITATION IN TOBACCO AND NICOTINE PRODUCTS | ALTRIA CLIENT SERVICES LLC (US) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160353795-A1 | ACYL NORNICOTINES REDUCE SENSORY IRRITATION IN TOBACCO AND NICOTINE PRODUCTS | NAPRT, AANAT, NAA50 | ALDH1A1 1181/4885CHRNA7 89/4885CHRNB2 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.