Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18695578 | 0.84 | HPGD (0.31) | ALOX15TP53MAPK1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL23120669 | 0.79 | LOXL2 (0.39) | ALOX15TP53MAPK1HSD17B10HPGD | |
| SCHEMBL5444047 | 0.79 | STK25 (0.35) | HPGDSMN1; SMN2 | |
| SCHEMBL7999472 | 0.79 | ALOX15 (0.39) | ALOX15TP53MAPK1HSD17B10HPGD | |
| SCHEMBL28189583 | 0.79 | ALOX15 (0.39) | ALOX15TP53MAPK1HSD17B10HPGD | |
| SCHEMBL24915517 | 0.78 | KDM5A (0.34) | — | |
| SCHEMBL30930296 | 0.73 | ALOX15 (0.37) | ALOX15TP53MAPK1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL25180560 | 0.71 | — | — | |
| SCHEMBL1531092 | 0.71 | ALOX15 (0.55) | ALOX15TP53MAPK1HSD17B10HPGD | |
| SCHEMBL28309056 | 0.71 | ALOX15 (0.33) | ALOX15TP53MAPK1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |
| EP-1503998-A1 | HETEROARYL SUBSTITUTED SPIROCYCLIC SUFAMIDES FOR INHIBITION OF GAMMA SECRETASE | MERCK SHARP & DOHME LTD. (GB) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003093252-A1 | HETEROARYL SUBSTITUTED SPIROCYCLIC SULFAMIDES FOR INHIBITION OF GAMMA SECRETASE | MERCK SHARP & DOHME LIMITED (GB) | 2003-11-13 | — | — | WO | disclosed |
| WO-2000071536-A1 | HETEROARYLOXYPYRIMIDINE INSECTICIDES AND ACARICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-11-30 | — | — | WO | disclosed |
| CN-1025141-C | Herbicidal compositions containing 5-heterocycle substituted oxazolidine dihaloacetamide antidotes and uses thereof | MONSANTO CO (US) | 1994-06-29 | — | — | CN | disclosed |
| US-5256626-A | Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds | MONSANTO COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-5225570-A | Plant safening agents for crops treated with herbicides | MONSANTO COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0304409-B1 | 5-HETEROCYCLIC-SUBSTITUTED OXAZOLIDINE HALOACETAMIDES | MONSANTO CO (US) | 1992-10-28 | — | — | EP | disclosed |
| CN-1031375-A | The oxazolidine dihaloacetamides class of 5-heterocyclic substituted | MONSANTO CO (US) | 1989-03-01 | — | — | CN | disclosed |
| EP-0304409-A1 | 5-Heterocyclic-substituted oxazolidine haloacetamides | MONSANTO COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |