Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829756 | 0.79 | ALOX15 (0.42) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23120669 | 0.79 | LOXL2 (0.39) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL7999472 | 0.79 | ALOX15 (0.39) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL8448440 | 0.71 | ALOX15 (0.42) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL10863685 | 0.71 | ALOX15 (0.33) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL6367872 | 0.71 | TP53 (0.43) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL28309056 | 0.71 | ALOX15 (0.33) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL30930296 | 0.70 | ALOX15 (0.37) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL27797795 | 0.69 | TP53 (0.32) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL6202182 | 0.69 | CA2 (0.39) | ALOX15TP53MAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408335-B | Pyrazolo pyrrolidin derivatives and its purposes in disease is treated | 诺华股份有限公司 | 2017-11-17 | — | — | CN | disclosed |