Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17219535 | 0.96 | MAPT (0.36) | MAPTPKMKCNH2MAPK1VCP | |
| SCHEMBL28077351 | 0.82 | ATM (0.35) | MAPTPKMMAPK1VCPATM | |
| SCHEMBL6141212 | 0.82 | MAPT (0.37) | MAPTPKMMAPK1VCPATM | |
| SCHEMBL3823580 | 0.81 | MAPT (0.36) | MAPTPKMMAPK1VCPATM | |
| SCHEMBL23580766 | 0.79 | MAPT (0.37) | MAPTPKMMAPK1VCPATM | |
| SCHEMBL17219320 | 0.78 | ALDH1A1 (0.44) | MAPTPKMMAPK1ATMTDP1 | |
| SCHEMBL17219091 | 0.78 | TSHR (0.44) | MAPTPKMMAPK1VCPATM | |
| SCHEMBL2897221 | 0.78 | GPR35 (0.41) | MAPTPKMMAPK1VCPTDP1 | |
| SCHEMBL1994831 | 0.75 | TDP1 (0.41) | ATMTDP1ALDH1A1HIF1ATSHR | |
| SCHEMBL24639499 | 0.75 | GRIN2D (0.50) | MAPTPKMMAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940002-B1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | NIPPON SODA CO (JP) | 2016-12-14 | — | — | EP | disclosed |