Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640826 | 0.82 | TSHR (0.48) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6141212 | 0.82 | MAPT (0.37) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17218388 | 0.81 | TSHR (0.63) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17219535 | 0.81 | MAPT (0.36) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23580766 | 0.79 | MAPT (0.37) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17219320 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17218955 | 0.78 | TSHR (0.44) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18298069 | 0.78 | TSHR (0.59) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18298070 | 0.78 | MAPT (0.34) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2897221 | 0.78 | GPR35 (0.41) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758468-B2 | Halogenated aniline and method for producing same | NIPPON SODA CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9573881-B2 | Halogenated aniline and method for producing same | NIPPON SODA CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20170029361-A1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-2940002-B1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | NIPPON SODA CO (JP) | 2016-12-14 | — | — | EP | disclosed |
| US-20150329472-A1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | NIPPON SODA CO., LTD. (JP) | 2015-11-19 | — | — | US | disclosed |
| EP-2940002-A1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | Nippon Soda Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029361-A1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | TPO, CYP1A2, XDH | TSHR 95/4885ALDH1A1 259/4885GRIN2D 2167/4885 |
| US-20150329472-A1 | HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME | TPO, CYP1A2, XDH | TSHR 95/4885ALDH1A1 259/4885GRIN2D 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.