Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341900 | 0.83 | LMNA (0.54) | TDP1KDM4EALDH1A1TSHRPKM | |
| SCHEMBL137002 | 0.81 | PKM (0.71) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29490828 | 0.81 | PKM (0.71) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL7175009 | 0.80 | PKM (0.70) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Water SCHEMBL20575696 | 0.80 | PKM (0.70) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| Water SCHEMBL6469488 | 0.80 | PKM (0.70) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7187750 | 0.80 | PKM (0.70) | TDP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6423993 | 0.79 | PKM (0.45) | TDP1KDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL341901 | 0.79 | KDM4E (0.49) | TDP1KDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL2453260 | 0.77 | PKM (0.38) | TDP1KDM4EALDH1A1HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| EP-1761490-B1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2011-09-07 | — | — | EP | claimed |
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | claimed |
| US-20050192182-A1 | Herbicidal mixtures based on substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | US | claimed |
| US-20040116294-A1 | Herbicides based on substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2004-06-17 | — | — | US | claimed |
| EP-2675277-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | Bayer Intellectual Property GmbH (DE) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110517-A1 | SYNERGISTIC COMBINATIONS CONTAINING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | WO | disclosed |
| CN-1198507-C | Selective herbicides based on substituted phenylsulfonylaminocarbonyltriazolinones and safeners | BAYER AG (DE) | 2005-04-27 | — | — | CN | disclosed |
| EP-1211941-B1 | SELECTIVE HERBICIDES ON THE BASIS OF A SUBSTITUTED PHENYLSULFONYLAMINOCARBONYLTRIAZOLINONE AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| CN-1379622-A | Selective herbicides based on substituted phenylsulfonylaminocarbonyltriazolinones and safeners | BAYER AG (DE) | 2002-11-13 | — | — | CN | disclosed |
| EP-1211941-A1 | SELECTIVE HERBICIDES ON THE BASIS OF A SUBSTITUTED PHENYLSULFONYLAMINOCARBONYLTRIAZOLINONE AND SAFENERS | Bayer Aktiengesellschaft (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001015533-A1 | SELECTIVE HERBICIDES ON THE BASIS OF A SUBSTITUTED PHENYLSULFONYLAMINOCARBONYLTRIAZOLINONE AND SAFENERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192182-A1 | Herbicidal mixtures based on substituted aryl ketones | DDT, CBR3, CYP1B1 | TDP1 1519/4885KDM4E 1246/4885ALDH1A1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.