Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423993 | 0.84 | PKM (0.45) | LMNAPKMSMN1; SMN2TSHRKDM4E | |
| SCHEMBL29452815 | 0.83 | PKM (0.74) | LMNAPKMSMN1; SMN2GAATSHR | |
| SCHEMBL1153422 | 0.83 | PKM (0.74) | LMNAPKMSMN1; SMN2GAATSHR | |
| SCHEMBL1830308 | 0.83 | TDP1 (0.54) | PKMTSHRKDM4EKMT2APTGDR | |
| SCHEMBL342666 | 0.79 | ALDH1A1 (0.46) | PKMSMN1; SMN2GAATSHRKDM4E | |
| SCHEMBL3989929 | 0.77 | KDM4E (0.52) | LMNAPKMSMN1; SMN2GAATSHR | |
| SCHEMBL27650217 | 0.76 | LMNA (0.38) | LMNAPKMSMN1; SMN2GAATSHR | |
| SCHEMBL2978955 | 0.76 | MAPT (0.65) | PKMSMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL5000233 | 0.74 | LMNA (0.55) | LMNAPKMSMN1; SMN2GAATSHR | |
| SCHEMBL3273629 | 0.74 | LMNA (0.64) | LMNASMN1; SMN2GAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| US-20070298966-A1 | Fungicidal Combinations of Active Ingredients | BAYERCROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | claimed |
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | US | claimed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | claimed |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | BAYER CROPSCIENCE AG (DE) | 2007-04-26 | — | — | US | claimed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | claimed |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | claimed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | BAYER CROPSCIENCE AG (DE) | 2005-03-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | LMNA 4367/4885PKM 928/4885SMN1; SMN2 4638/4885 |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | DDT, CYP4X1, HPD | LMNA 4727/4885PKM 1033/4885SMN1; SMN2 4748/4885 |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | WEE1, KCNE1, CCNE1 | LMNA 3663/4885PKM 12/4885SMN1; SMN2 4627/4885 |
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | AGXT, PAOX, DDT | LMNA 4028/4885PKM 366/4885SMN1; SMN2 3531/4885 |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | DDT, DDC, DAO | LMNA 4337/4885PKM 121/4885SMN1; SMN2 2872/4885 |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | LMNA 3066/4885PKM 649/4885SMN1; SMN2 4187/4885 |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | DDT, LAGE3, KYAT1 | LMNA 2890/4885PKM 33/4885SMN1; SMN2 4282/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | LMNA 4675/4885PKM 1663/4885SMN1; SMN2 1812/4885 |
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | DDT, HDHD5, TBCA | LMNA 3713/4885PKM 728/4885SMN1; SMN2 4295/4885 |
| US-20070298966-A1 | Fungicidal Combinations of Active Ingredients | DDT, CYP51A1, CYP4Z1 | LMNA 4469/4885PKM 2039/4885SMN1; SMN2 1057/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | LMNA 4048/4885PKM 306/4885SMN1; SMN2 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.