Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304646 | 0.83 | MAPK1 (0.41) | KDM4EALDH1A1L3MBTL1LMNACYP1A2 | |
| SCHEMBL14770746 | 0.76 | KMO (0.38) | HAO1HCAR2 | |
| SCHEMBL16887487 | 0.73 | TLR7 (0.41) | TLR7 | |
| SCHEMBL11023993 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1ALOX15HCAR2 | |
| SCHEMBL70035 | 0.70 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7170956 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL7767700 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| Water SCHEMBL336347 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| Water SCHEMBL28665454 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL11594387 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016198613-A1 | N-(THIO)ACYLIMINO COMPOUNDS | BASF SE (DE) | 2016-12-15 | — | — | WO | disclosed |