Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317272 | 0.85 | NOS3 (0.33) | NOS3NOS1NOS2POLQFGFR1 | |
| SCHEMBL16887480 | 0.73 | DRD2 (0.46) | TLR7 | |
| SCHEMBL18304650 | 0.73 | KDM4E (0.40) | TLR7 | |
| SCHEMBL29313297 | 0.73 | NOS3 (0.33) | NOS3NOS1NOS2POLQFGFR1 | |
| SCHEMBL17567286 | 0.72 | GRM5 (0.45) | TLR7TLR8 | |
| SCHEMBL23627444 | 0.71 | NOS3 (0.31) | NOS3NOS1NOS2 | |
| SCHEMBL18304646 | 0.69 | MAPK1 (0.41) | — | |
| SCHEMBL617257 | 0.69 | ALOX5AP (0.35) | POLQ | |
| SCHEMBL30525699 | 0.68 | SMN1; SMN2 (0.40) | NOS1 | |
| SCHEMBL24538233 | 0.68 | SMN1; SMN2 (0.40) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101958-A2 | NOVEL INHIBITORS OF GLUTAMINASE | RHIZEN PHARMACEUTICALS SA (CH) | 2015-07-09 | — | — | WO | disclosed |