Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572063 | 0.93 | KMO (0.46) | CREBBPTSHRRARGRARBSMN1; SMN2 | |
| SCHEMBL18304697 | 0.91 | KMO (0.53) | CREBBPTSHRSMN1; SMN2TDP1GAA | |
| SCHEMBL10148368 | 0.85 | CREBBP (0.50) | CREBBPTSHRRARGRARBSMN1; SMN2 | |
| SCHEMBL26091247 | 0.82 | CHRNA1 (0.42) | MEN1KMT2A | |
| SCHEMBL26091255 | 0.82 | CHRNA1 (0.42) | MEN1KMT2A | |
| SCHEMBL10148390 | 0.82 | RARG (0.56) | CREBBPTSHRRARGRARBGAA | |
| SCHEMBL16951962 | 0.81 | HTR2C (0.36) | CREBBPRARGRARBTDP1ALDH1A1 | |
| SCHEMBL2502725 | 0.81 | SLC6A3 (0.48) | SMN1; SMN2TDP1GAAALOX15HSD17B10 | |
| SCHEMBL14273030 | 0.79 | CA12 (0.55) | CREBBPTSHRRARGRARBGAA | |
| SCHEMBL29154739 | 0.79 | KDM4E (0.46) | CREBBPTSHRRARGRARBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265055-A1 | STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS | OXFORD FINANCE LLC | 2023-08-24 | — | — | US | disclosed |
| WO-2021178857-A1 | ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF | JANPIX, LTD. (US) | 2021-09-10 | — | — | WO | disclosed |
| WO-2021178907-A1 | STAT INHIBITORY COMPOUNDS AND COMPOSITIONS | JANPIX, LTD. (US) | 2021-09-10 | — | — | WO | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-2000540-A9 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2000540-A2 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | CREBBP 2909/4885TSHR 4189/4885RARG 4586/4885 |
| US-20230265055-A1 | STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS | STAT5B, STAT5A, STAT3 | CREBBP 13/4885TSHR 1093/4885RARG 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.