Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304697 | 0.95 | KMO (0.53) | KMOGAASMN1; SMN2TSHRTDP1 | |
| SCHEMBL10148085 | 0.93 | CREBBP (0.47) | KMOGAASMN1; SMN2TSHRTDP1 | |
| SCHEMBL4946903 | 0.83 | KMO (0.54) | KMOGAASMN1; SMN2TSHRTDP1 | |
| SCHEMBL4951622 | 0.81 | KMO (0.57) | KMOGAASMN1; SMN2TSHRTDP1 | |
| SCHEMBL29470084 | 0.81 | CAMKK2 (0.49) | KMOALDH1A1 | |
| SCHEMBL14273033 | 0.81 | KDM4E (0.52) | KMOGAACREBBPHTTALDH1A1 | |
| SCHEMBL2445552 | 0.81 | CAMKK2 (0.49) | KMOALDH1A1 | |
| SCHEMBL26091255 | 0.80 | CHRNA1 (0.42) | — | |
| SCHEMBL26091247 | 0.80 | CHRNA1 (0.42) | — | |
| SCHEMBL10148368 | 0.79 | CREBBP (0.50) | KMOGAASMN1; SMN2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452679-A1 | CYTOPROTECTIVE AGENT | National University Corporation Tokyo University Of Agriculture and Technology (JP) | 2012-05-16 | — | — | EP | disclosed |