Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.58 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456323 | 0.90 | SLC5A1 (0.72) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL1682159 | 0.84 | NFKB1 (0.83) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL18306242 | 0.82 | SLC5A1 (0.55) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL14071710 | 0.81 | CYP19A1 (0.82) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL4742840 | 0.80 | NFKB1 (0.80) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL7332474 | 0.79 | TAAR1 (0.61) | HDAC1HDAC6MTNR1AMTNR1BTAAR1 | |
| SCHEMBL15457885 | 0.78 | NFKB1 (0.83) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL457498 | 0.78 | SLC5A1 (0.70) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL18306234 | 0.77 | SLC5A1 (0.84) | NFKB1NFKB2RELASLC5A1SLC5A2 | |
| SCHEMBL346302 | 0.77 | FFAR1 (0.65) | GAAHDAC1HDAC6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517994-B2 | Antibacterial agents: phloroglucinol derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-13 | — | — | US | disclosed |