SCHEMBL4742840

SCHEMBL4742840

COc1cc(O)c(C(=O)CCc2ccccc2)c(O)c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.80
NFKB2 Q00653 2/20 0.80
RELA Q04206 2/20 0.80
SLC5A1 P13866 7/20 0.77
SLC5A2 P31639 7/20 0.77
GAA P10253 4/20 0.77
MAPT P10636 2/20 0.77
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
TDP1 Q9NUW8 2/20 0.60
CBS P35520 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
CYP19A1 P11511 4/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
KDM4E B2RXH2 1/20 0.59
MEN1 O00255 1/20 0.59
SLC16A3 O15427 1/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968230 0.93 NFKB1 (0.69) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL29435841 0.91 NFKB1 (0.68) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL1937964 0.91 NFKB1 (0.68) NFKB1NFKB2RELASLC5A1SLC5A2
Asebogenin SCHEMBL4740064 0.89 NFKB1 (0.88) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL5084404 0.89 NFKB1 (1.00) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL455029 0.87 SLC5A1 (1.00) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL15457885 0.86 NFKB1 (0.83) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL1938569 0.85 SLC5A1 (0.73) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL28968233 0.85 NFKB1 (0.59) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL17502354 0.84 RAB9A (0.60) NFKB1NFKB2RELASLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10695283-B2 Extract of Greyia radlkoferi and use thereof UNIVERSITY OF PRETORIA (ZA) 2020-06-30 US claimed
US-20180071204-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF KWAZULU-NATAL (ZA) 2018-03-15 US claimed
EP-2849768-B1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIV PRETORIA (ZA) 2016-06-01 EP claimed
US-20150118337-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2015-04-30 US claimed
CN-122005634-A Compound antibacterial gel of herba Pileae Scriptae, and preparation method and application thereof 贵州盛世泰合医药科技有限公司 2026-05-12 CN disclosed
US-12569530-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-03-10 US disclosed
US-12453799-B1 Bioadhesive for medical and dental applications IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-10-28 US disclosed
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-08-07 US disclosed
US-12318422-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-06-03 US disclosed
US-20240293492-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-09-05 US disclosed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
US-20150118337-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2015-04-30 US disclosed
CN-104582713-A Grignard family feijie extract and application thereof UNIV PRETORIA 2015-04-29 CN disclosed
EP-2849768-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF University of Pretoria (ZA) 2015-03-25 EP disclosed
EP-2849768-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF University of Pretoria (ZA) 2015-03-25 EP disclosed
US-20140023721-A1 METHOD OF EXTRACTING ACTIVE MOLECULES FROM NATURAL RESINS AND USE THEREOF RODE PHARMA S.R.L. (IT) 2014-01-23 US disclosed
WO-2013171720-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2013-11-21 WO disclosed
WO-2013171720-A1 EXTRACT OF GREYIA RADLKOFERI AND USE THEREOF UNIVERSITY OF PRETORIA (ZA) 2013-11-21 WO disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER UGGT1, G6PD, UGT1A3 NFKB1 1450/4885NFKB2 2221/4885RELA 414/4885
US-20240293492-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL UGGT1, G6PD, UGDH NFKB1 684/4885NFKB2 1141/4885RELA 425/4885
US-12569530-B2 Tannin-based antiproliferative pharmaceutical SLC2A3, SLC2A1, SLC2A8 NFKB1 892/4885NFKB2 949/4885RELA 542/4885
US-12318422-B2 Tannin-based antiproliferative pharmaceutical UGGT1, G6PD, UGDH NFKB1 684/4885NFKB2 1141/4885RELA 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.