Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308554 | 0.89 | BRD4 (0.32) | CYP1A2PDE10A | |
| SCHEMBL18308391 | 0.84 | BRD4 (0.31) | — | |
| SCHEMBL18308505 | 0.78 | MAPT (0.34) | METFGFR1SRC | |
| SCHEMBL18308334 | 0.77 | MAPT (0.33) | — | |
| SCHEMBL18308325 | 0.77 | KDM4E (0.35) | MET | |
| SCHEMBL18308331 | 0.75 | RECQL (0.35) | TSHRCYP1A2PDE10A | |
| SCHEMBL18308509 | 0.75 | PLK1 (0.38) | TSHRPDE10A | |
| SCHEMBL18308333 | 0.74 | LCK (0.32) | — | |
| SCHEMBL18308538 | 0.73 | VCP (0.32) | — | |
| SCHEMBL20373756 | 0.62 | BRD4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |