Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308334 | 0.82 | MAPT (0.33) | — | |
| SCHEMBL18308543 | 0.80 | BRD4 (0.30) | — | |
| SCHEMBL18308342 | 0.80 | PDE2A (0.36) | PLK1 | |
| SCHEMBL18308504 | 0.80 | MET (0.36) | PDGFRBPDGFRAPLK1 | |
| SCHEMBL18308416 | 0.80 | GAA (0.33) | — | |
| SCHEMBL18308542 | 0.80 | PLK1 (0.32) | PLK1 | |
| SCHEMBL18308540 | 0.79 | MRGPRX4 (0.32) | — | |
| SCHEMBL18308550 | 0.79 | HPGDS (0.31) | — | |
| SCHEMBL18308505 | 0.79 | MAPT (0.34) | — | |
| SCHEMBL18308325 | 0.78 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |