Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308334 | 0.89 | MAPT (0.33) | MAPT | |
| SCHEMBL18308505 | 0.88 | MAPT (0.34) | LCKMAPT | |
| SCHEMBL18308388 | 0.87 | CASP3 (0.35) | MAPT | |
| SCHEMBL18308537 | 0.86 | MAPT (0.36) | MAPT | |
| SCHEMBL18308331 | 0.85 | RECQL (0.35) | MAPT | |
| SCHEMBL18308416 | 0.84 | GAA (0.33) | MAPT | |
| SCHEMBL18308542 | 0.84 | PLK1 (0.32) | MAPT | |
| SCHEMBL18308342 | 0.84 | PDE2A (0.36) | MAPT | |
| SCHEMBL18308539 | 0.83 | MET (0.37) | MAPT | |
| SCHEMBL18308504 | 0.82 | MET (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |