Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308810 | 0.92 | HTR7 (0.35) | HTR7ESR2FFAR1AKR1C3AKR1C2 | |
| SCHEMBL18308778 | 0.90 | HTR7 (0.36) | HTR7ESR2FFAR1ALDH2ESR1 | |
| SCHEMBL18308755 | 0.90 | RARB (0.35) | ESR2PPARGPPARAESR1WNT3A | |
| SCHEMBL18806015 | 0.89 | HTR7 (0.38) | HTR7ESR2FFAR1AKR1C3AKR1C2 | |
| SCHEMBL18308728 | 0.84 | RARB (0.36) | ESR2PPARGPPARAESR1 | |
| SCHEMBL18308735 | 0.84 | RARB (0.36) | ESR2PPARGPPARAESR1WNT3A | |
| SCHEMBL18308805 | 0.83 | HTR7 (0.41) | HTR7ESR2FFAR1ALDH2AKR1C3 | |
| SCHEMBL18308757 | 0.83 | RARB (0.35) | ESR2PPARGPPARAESR1WNT3A | |
| SCHEMBL18308764 | 0.83 | RARB (0.35) | ESR2PPARGPPARAESR1 | |
| SCHEMBL18806012 | 0.83 | ESR2 (0.33) | HTR7ESR2AKR1C3AKR1C2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | HTR7 4174/4885ESR2 4146/4885FFAR1 4194/4885 |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LCP1, MAP1LC3C | HTR7 3960/4885ESR2 4322/4885FFAR1 3886/4885 |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | HTR7 4122/4885ESR2 4381/4885FFAR1 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.