SCHEMBL183103

SCHEMBL183103

O=S(=O)(O)CCCCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.45
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
HDAC4 P56524 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
HDAC1 Q13547 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31461254 1.00 HDAC3 (0.45) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL182696 0.95 SIGMAR1 (0.46) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL31243457 0.95 SIGMAR1 (0.46) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9106500 0.94 SIGMAR1 (0.45) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9106576 0.84 PIM1 (0.50) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9103613 0.84 P2RX4 (0.46) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9106163 0.84 P2RX4 (0.46) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9099180 0.84 PIM1 (0.42) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9101900 0.84 AHR (0.40) HDAC3TUBB4ATUBBTUBA3CHDAC4
SCHEMBL9102744 0.84 PIM1 (0.59) HDAC3TUBB4ATUBBTUBA3CHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11573183-B2 Chemiluminescent substrates for peroxidase with extended shelf-life CYANAGEN S.R.L. (IT) 2023-02-07 US claimed
EP-3855185-B1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE CYANAGEN SRL (IT) 2022-07-06 EP claimed
US-20210231572-A1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE CYANAGEN S.R.L. (IT) 2021-07-29 US claimed
EP-3855185-A1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE Cyanagen Srl (IT) 2021-07-28 EP claimed
CN-113150775-A Peroxidase chemiluminescent substrate with extended shelf life 喜雅纳肯有限公司 2021-07-23 CN claimed
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US claimed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US claimed
US-RE49466-E1 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2023-03-21 US disclosed
US-11573183-B2 Chemiluminescent substrates for peroxidase with extended shelf-life CYANAGEN S.R.L. (IT) 2023-02-07 US disclosed
EP-3855185-B1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE CYANAGEN SRL (IT) 2022-07-06 EP disclosed
US-20210231572-A1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE CYANAGEN S.R.L. (IT) 2021-07-29 US disclosed
EP-3855185-A1 CHEMILUMINESCENT SUBSTRATES FOR PEROXIDASE WITH EXTENDED SHELF-LIFE Cyanagen Srl (IT) 2021-07-28 EP disclosed
CN-113150775-A Peroxidase chemiluminescent substrate with extended shelf life 喜雅纳肯有限公司 2021-07-23 CN disclosed
US-6858733-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2005-02-22 US disclosed
EP-1456176-A4 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN INC (US) 2004-11-03 EP disclosed
EP-1456176-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2004-09-15 EP disclosed
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2004-09-09 US disclosed
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2003-09-11 US disclosed
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase AKHAVAN-TAFTI HASHEM (US) 2003-09-11 US disclosed
WO-2003053934-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885TUBB4A 2025/4885TUBB 2553/4885
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885TUBB4A 2025/4885TUBB 2553/4885
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885TUBB4A 2025/4885TUBB 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.