Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BMI1 | P35226 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456019 | 0.87 | MAPK1 (0.37) | POLBRECQLL3MBTL1ALDH1A1PDE10A | |
| SCHEMBL18156768 | 0.84 | PSMD14 (0.35) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL20248522 | 0.81 | ALDH1A1 (0.41) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL18314563 | 0.80 | ESR1 (0.34) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL18456026 | 0.79 | ESR1 (0.37) | POLBRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL25648701 | 0.79 | POLB (0.39) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL18156777 | 0.78 | ALDH1A1 (0.34) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL20248524 | 0.78 | ALDH1A1 (0.38) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL21392432 | 0.78 | POLB (0.41) | PSMD14POLBRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL25728497 | 0.77 | PSMD14 (0.39) | PSMD14POLBRECQLL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208401-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-12-28 | — | — | US | disclosed |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
| WO-2016198144-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208401-B2 | Materials for organic electroluminescent devices | DDT, CELF2, BRD3 | PSMD14 3451/4885POLB 3761/4885RECQL 2769/4885 |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CELF2, BRD3 | PSMD14 3451/4885POLB 3761/4885RECQL 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.