SCHEMBL18314731

SCHEMBL18314731

C=CC(=O)Nc1ccc(CN(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 10/20 0.59
▸ THRA P10827 1/20 0.57
▸ THRB P10828 1/20 0.57
▸ F13A1 P00488 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ TGM1 P22735 1/20 0.54
▸ TGM3 Q08188 1/20 0.54
▸ LSS P48449 1/20 0.51
▸ HDAC3 O15379 1/20 0.50
▸ HDAC6 Q9UBN7 1/20 0.50
▸ EGFR P00533 1/20 0.47
▸ HRH3 Q9Y5N1 1/20 0.46
▸ JAK3 P52333 1/20 0.46
▸ BTK Q06187 1/20 0.46
▸ GSTO1 P78417 1/20 0.46
▸ MAOA P21397 1/20 0.45
▸ MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132464 0.81 THRA (0.67) TGM2THRATHRBF13A1LMNA
SCHEMBL440756 0.80 TGM2 (0.63) TGM2THRATHRBF13A1LMNA
SCHEMBL11436461 0.80 TGM2 (0.63) TGM2LMNALSSHDAC3HDAC6
SCHEMBL439369 0.80 TGM2 (0.79) TGM2THRATHRBF13A1LMNA
SCHEMBL16242100 0.79 TGM2 (0.61) TGM2THRATHRBF13A1LMNA
SCHEMBL1191835 0.79 TGM2 (0.61) TGM2THRATHRBF13A1LMNA
SCHEMBL12832351 0.78 THRB (0.77) TGM2THRATHRBF13A1LMNA
SCHEMBL20691200 0.78 TGM2 (0.61) TGM2THRATHRBF13A1LMNA
SCHEMBL25293287 0.77 TGM2 (0.59) TGM2THRATHRBF13A1LMNA
SCHEMBL1497339 0.77 TGM2 (0.59) TGM2THRATHRBF13A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790338-B2 Ion exchange membrane and method for manufacturing the same FUJIFILM CORPORATION (JP) 2017-10-17 — — US disclosed
US-20160362526-A1 ION EXCHANGE MEMBRANE AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2016-12-15 — — US disclosed
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