SCHEMBL440756

SCHEMBL440756

C=CC(=O)Nc1ccc(Cc2ccc(NC(=O)C=C)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 12/20 0.63
LMNA P02545 2/20 0.63
F13A1 P00488 2/20 0.63
TGM1 P22735 2/20 0.63
TGM3 Q08188 1/20 0.63
THRA P10827 1/20 0.61
THRB P10828 1/20 0.61
POLB P06746 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SAE1 Q9UBE0 2/20 0.47
UBA2 Q9UBT2 2/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29157753 0.93 TGM2 (0.70) TGM2LMNAF13A1TGM1TGM3
SCHEMBL439369 0.87 TGM2 (0.79) TGM2LMNAF13A1TGM1TGM3
SCHEMBL16242100 0.86 TGM2 (0.61) TGM2LMNAF13A1TGM1TGM3
SCHEMBL1191835 0.86 TGM2 (0.61) TGM2LMNAF13A1TGM1TGM3
SCHEMBL20691200 0.85 TGM2 (0.61) TGM2LMNAF13A1TGM1TGM3
SCHEMBL25293287 0.85 TGM2 (0.59) TGM2LMNAF13A1TGM1TGM3
SCHEMBL6279031 0.85 TGM2 (0.59) TGM2LMNAF13A1TGM1TGM3
SCHEMBL1132464 0.85 THRA (0.67) TGM2LMNAF13A1TGM1TGM3
SCHEMBL16653882 0.85 TGM2 (0.59) TGM2LMNAF13A1TGM1TGM3
SCHEMBL1497339 0.85 TGM2 (0.59) TGM2LMNAF13A1TGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160038888-A1 ION EXCHANGE MEMBRANES SELECTIVELY PERMEABLE TO SPECIFIC IONS SALTWORKS TECHNOLOGIES INC. (CA) 2016-02-11 US claimed
US-8470901-B2 Organic aerogel and composition and method for manufacturing the organic aerogel SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-25 US claimed
US-20120064287-A1 AEROGEL COMPOSITE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-15 US claimed
US-20110071231-A1 ORGANIC AEROGEL AND COMPOSITION AND METHOD FOR MANUFACTURING THE ORGANIC AEROGEL SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-24 US claimed
EP-2909168-B1 ACRYLAMIDE-BASED CROSSLINKING MONOMERS, THEIR PREPARATION, AND USES THEREOF SALTWORKS TECH INC (CA) 2018-05-09 EP disclosed
US-9662647-B2 Acrylamide-based crosslinking monomers, their preparation, and uses thereof SALTWORKS TECHNOLOGIES INC. (CA) 2017-05-30 US disclosed
US-20160318013-A1 Acrylamide-Based Crosslinking Monomers, Their Preparation, And Uses Thereof SALTWORKS TECHNOLOGIES INC. (CA) 2016-11-03 US disclosed
US-9416239-B2 Acrylamide-based crosslinking monomers, their preparation, and uses thereof SALTWORKS TECHNOLOGIES INC. (CA) 2016-08-16 US disclosed
US-20160038888-A1 ION EXCHANGE MEMBRANES SELECTIVELY PERMEABLE TO SPECIFIC IONS SALTWORKS TECHNOLOGIES INC. (CA) 2016-02-11 US disclosed
EP-2909168-A1 ACRYLAMIDE-BASED CROSSLINKING MONOMERS, THEIR PREPARATION, AND USES THEREOF Saltworks Technologies Inc. (CA) 2015-08-26 EP disclosed
US-20150232627-A1 Acrylamide-Based Crosslinking Monomers, Their Preparation, And Uses Thereof SALTWORKS TECHNOLOGIES INC. (CA) 2015-08-20 US disclosed
WO-2014165984-A1 ION EXCHANGE MEMBRANES SELECTIVELY PERMEABLE TO SPECIFIC IONS SALTWORKS TECHNOLOGIES INC. (CA) 2014-10-16 WO disclosed
US-20120064287-A1 AEROGEL COMPOSITE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-15 US disclosed
US-20120065421-A1 NOVEL METHOD OF SYNTHESIZING FENOFIBRATE SYNKEM (FR) 2012-03-15 US disclosed
US-20120064287-A1 AEROGEL COMPOSITE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-15 US disclosed
US-20120064287-A1 AEROGEL COMPOSITE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-15 US disclosed
EP-2397513-A2 Aerogel-Foam Composites SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-12-21 EP disclosed
US-20110071231-A1 ORGANIC AEROGEL AND COMPOSITION AND METHOD FOR MANUFACTURING THE ORGANIC AEROGEL SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-24 US disclosed
US-20110071231-A1 ORGANIC AEROGEL AND COMPOSITION AND METHOD FOR MANUFACTURING THE ORGANIC AEROGEL SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-24 US disclosed
US-20110071231-A1 ORGANIC AEROGEL AND COMPOSITION AND METHOD FOR MANUFACTURING THE ORGANIC AEROGEL SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318013-A1 Acrylamide-Based Crosslinking Monomers, Their Preparation, And Uses Thereof ACR, ALAD, IDH1 TGM2 3072/4885LMNA 1952/4885F13A1 188/4885
US-20120065421-A1 NOVEL METHOD OF SYNTHESIZING FENOFIBRATE DECR2, HSD17B4, CYP4F11 TGM2 3709/4885LMNA 1600/4885F13A1 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.