Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | HINT1 | P49773 | 1/20 | 0.48 |
| ▸ | AMD1 | P17707 | 2/20 | 0.48 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18314786 | 0.92 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18314801 | 0.86 | HINT1 (0.62) | PI4KAPI4K2BPI4K2API4KBHINT1 | |
| SCHEMBL18314956 | 0.85 | ADORA3 (0.50) | HINT1EPRS1DNMT1 | |
| SCHEMBL18314858 | 0.81 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL30238879 | 0.81 | RXFP1 (0.51) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18314805 | 0.81 | POLB (0.48) | HINT1EPRS1DNMT1 | |
| SCHEMBL7037167 | 0.79 | RXFP1 (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL2291619 | 0.78 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18314780 | 0.78 | HINT1 (0.60) | HINT1EPRS1 | |
| SCHEMBL18314781 | 0.78 | HINT1 (0.60) | HINT1EPRS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201374-A1 | SULFANIDE ADENOSINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-15 | — | — | WO | disclosed |