Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.60 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.52 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18314781 | 1.00 | HINT1 (0.60) | HINT1EPRS1IMPDH2IMPDH1 | |
| SCHEMBL18314801 | 0.91 | HINT1 (0.62) | HINT1EPRS1IMPDH2IMPDH1 | |
| SCHEMBL18314785 | 0.88 | EPRS1 (0.48) | HINT1EPRS1 | |
| SCHEMBL31533324 | 0.87 | EPRS1 (0.76) | HINT1EPRS1 | |
| SCHEMBL18314782 | 0.87 | EPRS1 (0.76) | HINT1EPRS1 | |
| SCHEMBL18314786 | 0.87 | PI4KA (0.55) | HINT1EPRS1 | |
| SCHEMBL18314956 | 0.79 | ADORA3 (0.50) | HINT1EPRS1 | |
| SCHEMBL7102573 | 0.78 | DPP4 (0.69) | — | |
| SCHEMBL20711309 | 0.78 | TRPM2 (0.66) | — | |
| SCHEMBL18314784 | 0.78 | PI4KA (0.58) | HINT1EPRS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201374-A1 | SULFANIDE ADENOSINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-15 | — | — | WO | disclosed |