Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATXN2 | Q99700 | 6/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.68 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NUDT15 | Q9NV35 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | USP9X | Q93008 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422072 | 0.83 | ALPL (0.64) | ATXN2ENPP2ALPLKMT2AMEN1 | |
| SCHEMBL21313825 | 0.82 | ALPL (0.62) | ATXN2ENPP2ALPLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL16616243 | 0.82 | ALPL (0.62) | ATXN2ENPP2ALPLKMT2AMEN1 | |
| SCHEMBL15540234 | 0.81 | ENPP2 (1.00) | ATXN2ENPP2 | |
| SCHEMBL23122311 | 0.80 | ATXN2 (0.50) | ATXN2ENPP2CYP2C19 | |
| SCHEMBL18315538 | 0.79 | ENPP2 (0.61) | ATXN2ENPP2KMT2AMEN1TSHR | |
| SCHEMBL15584191 | 0.79 | ENPP2 (0.67) | ATXN2ENPP2NUDT15 | |
| SCHEMBL15541318 | 0.77 | ENPP2 (1.00) | ATXN2ENPP2 | |
| SCHEMBL18315557 | 0.77 | ATXN2 (0.68) | ATXN2ENPP2TSHR | |
| SCHEMBL26434400 | 0.76 | ALPL (0.68) | ALPLKMT2AMEN1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861566-B1 | NEW DIAZASPIROCYCLOALKANE AND AZASPIROCYCLOALKANE | HOFFMANN LA ROCHE (CH) | 2016-12-21 | — | — | EP | claimed |