Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NUDT15 | Q9NV35 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21313825 | 0.80 | ALPL (0.62) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL27771176 | 0.80 | ALPL (0.65) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL18315571 | 0.76 | ATXN2 (0.68) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL118595 | 0.75 | KMT2A (0.56) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL23246000 | 0.75 | MAPT (0.61) | KMT2AMEN1MAPTLMNATSHR | |
| SCHEMBL31141476 | 0.75 | MAPT (0.61) | KMT2AMEN1MAPTLMNATSHR | |
| SCHEMBL2989702 | 0.74 | ALPL (0.62) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL18464328 | 0.73 | ENPP2 (0.79) | ALPLKMT2AMEN1MAPTLMNA | |
| SCHEMBL1626449 | 0.73 | KMT2A (0.65) | ALPLKMT2AMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL1627652 | 0.73 | KMT2A (0.64) | ALPLKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128889-A1 | REL/RELA/SPOT SMALL MOLECULES MODULATORS AND SCREENING METHODS | Université Libre de Bruxelles (BE) | 2023-04-27 | — | — | US | disclosed |
| US-20230128889-A1 | REL/RELA/SPOT SMALL MOLECULES MODULATORS AND SCREENING METHODS | Université Libre de Bruxelles (BE) | 2023-04-27 | — | — | US | disclosed |