Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438214 | 0.76 | RAB9A (0.70) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL29399796 | 0.76 | RAB9A (0.61) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL10793724 | 0.76 | RAB9A (0.59) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL2226467 | 0.76 | RAB9A (0.59) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL525427 | 0.76 | RAB9A (0.61) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL1185009 | 0.76 | NPC1 (0.63) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL2682040 | 0.75 | RAB9A (0.71) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL11318736 | 0.74 | RAB9A (0.59) | NPC1RAB9APKMNPSR1GAA | |
| Hydrochloric Acid SCHEMBL31091390 | 0.74 | RAB9A (0.59) | NPC1RAB9APKMNPSR1GAA | |
| SCHEMBL22839376 | 0.74 | NPC1 (0.52) | NPC1RAB9APKMNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753457-B1 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RES & DEV (IL) | 2016-08-10 | — | — | EP | disclosed |
| EP-2322173-B1 | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RES & DEV (IL) | 2016-08-10 | — | — | EP | disclosed |
| US-8207154-B2 | Palladium 31-oxo-15- methoxycarbonylmethyl- Rhodobacteriochlorin-131-(2-N3- trimethylammoniumethyl)amide acetate (salt); bacteriochlorophylls free of carbamate group; as photosensitizer for thermodynamic therapy and diagnosis; cancer, age related macular degeneration; killing viruses and bacteria | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2012-06-26 | — | — | US | disclosed |
| EP-2322173-A1 | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2011-05-18 | — | — | EP | disclosed |
| US-20080076748-A1 | Catatonic Bacteriochlorophyll Derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-03-27 | — | — | US | disclosed |
| EP-1753457-A2 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO., Ltd. (IL) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005120573-A2 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076748-A1 | Catatonic Bacteriochlorophyll Derivatives | CAT, PPOX, SCLY | NPC1 4331/4885RAB9A 4262/4885PKM 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.