Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.76 |
| ▸ | PTGES | O14684 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | CASP7 | P55210 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | EPRS1 | P07814 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117422 | 0.92 | PTGES (0.84) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL117430 | 0.91 | EPRS1 (0.79) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL5529524 | 0.88 | HSD17B10 (0.94) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL5530291 | 0.87 | EPRS1 (0.85) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL12237494 | 0.87 | RXFP1 (0.75) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL1899098 | 0.87 | RXFP1 (0.79) | DHODHALDH1A1HPGDHIF1AHSD17B10 | |
| SCHEMBL5838639 | 0.86 | DHODH (0.74) | DHODHALDH1A1HPGDHSD17B10EPRS1 | |
| SCHEMBL14286200 | 0.85 | HSD17B10 (1.00) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL31590457 | 0.85 | PTGES (0.68) | DHODHPTGESALDH1A1ALOX5CYP2C9 | |
| SCHEMBL7814193 | 0.84 | GAA (0.71) | DHODHALDH1A1CYP2C9HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |