Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.75 |
| ▸ | DHODH | Q02127 | 4/20 | 0.72 |
| ▸ | EPRS1 | P07814 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899098 | 0.97 | RXFP1 (0.79) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL117430 | 0.93 | EPRS1 (0.79) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL12237496 | 0.92 | RXFP1 (0.67) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL5530291 | 0.89 | EPRS1 (0.85) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL5838639 | 0.87 | DHODH (0.74) | RXFP1DHODHEPRS1HSD17B10KDM4E | |
| SCHEMBL18320549 | 0.87 | DHODH (0.76) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL1898124 | 0.87 | KDM4E (0.72) | RXFP1DHODHEPRS1HSD17B10HIF1A | |
| SCHEMBL7814193 | 0.86 | GAA (0.71) | RXFP1DHODHEPRS1HSD17B10KDM4E | |
| SCHEMBL29788463 | 0.85 | DHODH (0.80) | DHODHEPRS1TP53KDM4ELMNA | |
| SCHEMBL116022 | 0.85 | DHODH (0.80) | DHODHEPRS1TP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710079-B2 | Quinoline compounds and their use for treating viral infection | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2014-04-29 | — | — | US | disclosed |
| US-8710079-B2 | Quinoline compounds and their use for treating viral infection | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2014-04-29 | — | — | US | disclosed |
| US-20110263620-A1 | QUINOLINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTION | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-10-27 | — | — | US | disclosed |
| US-20110263620-A1 | QUINOLINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTION | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263620-A1 | QUINOLINE COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTION | RECQL, IFNG, NQO2 | RXFP1 789/4885DHODH 1914/4885EPRS1 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.