Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | P4HB | P07237 | 1/20 | 0.74 |
| ▸ | DHODH | Q02127 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117430 | 0.93 | EPRS1 (0.79) | EPRS1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL12237494 | 0.89 | RXFP1 (0.75) | EPRS1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL1899098 | 0.88 | RXFP1 (0.79) | EPRS1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL18320549 | 0.87 | DHODH (0.76) | EPRS1ALDH1A1GAADHODHPOLB | |
| SCHEMBL5838639 | 0.87 | DHODH (0.74) | EPRS1ALDH1A1GAAMAPTDHODH | |
| SCHEMBL7814193 | 0.86 | GAA (0.71) | EPRS1ALDH1A1GAAMAPTDHODH | |
| SCHEMBL18320787 | 0.85 | KDM4E (0.71) | EPRS1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL18320678 | 0.84 | DHODH (0.70) | EPRS1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL3232504 | 0.83 | DHODH (0.80) | EPRS1ALDH1A1GAADHODHPOLB | |
| SCHEMBL5792900 | 0.82 | DHODH (0.78) | EPRS1ALDH1A1GAADHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | EPRS1 4473/4885ALDH1A1 4554/4885GAA 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.