SCHEMBL18321998

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29405721	1.00	CYP19A1 (0.49)	CYP19A1DGAT1ITGB3ITGA2BCYP26A1
	SCHEMBL9638064	0.87	CYP19A1 (0.64)	CYP19A1DGAT1ITGB3ITGA2BCYP26A1
	SCHEMBL6067801	0.85	METAP1 (0.46)	CYP19A1DGAT1ITGB3ITGA2BFFAR1
	SCHEMBL20255760	0.84	CYP19A1 (0.43)	CYP19A1DGAT1CYP26A1TDP1L3MBTL1
	SCHEMBL10662181	0.83	DGAT1 (0.51)	CYP19A1DGAT1ITGB3ITGA2BCYP26A1
	SCHEMBL18322010	0.82	HSD17B1 (0.42)	CYP19A1CYP26A1
	SCHEMBL28601267	0.81	FFAR1 (0.50)	FFAR1
	SCHEMBL28601201	0.81	FFAR1 (0.50)	FFAR1
	SCHEMBL10686519	0.80	CYP19A1 (0.59)	CYP19A1CYP26A1TDP1L3MBTL1
	SCHEMBL29679345	0.80	CYP19A1 (0.59)	CYP19A1CYP26A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.