SCHEMBL18322690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3406057	0.87	HDAC3 (0.39)	ALDH1A1HSD17B10KDM4EHDAC3HDAC1
	SCHEMBL2325513	0.86	HPGD (0.36)	ALDH1A1KDM4EMAPT
	SCHEMBL8605151	0.84	HDAC3 (0.40)	L3MBTL1KDM4EHDAC3HDAC1HDAC2
	SCHEMBL1052780	0.83	HDAC3 (0.53)	ALDH1A1HSD17B10L3MBTL1SMN1; SMN2HDAC3
	SCHEMBL16269396	0.83	SLC6A2 (0.50)	ALDH1A1L3MBTL1KDM4E
	SCHEMBL18322761	0.81	SNCA (0.43)	MAPT
	SCHEMBL27829838	0.80	HDAC3 (0.37)	ALDH1A1HSD17B10L3MBTL1KDM4EHDAC3
	SCHEMBL10556095	0.79	ALDH1A1 (0.59)	ALDH1A1HSD17B10SMN1; SMN2KDM4EMAPT
	SCHEMBL18758783	0.78	CA12 (0.43)	ALDH1A1HSD17B10L3MBTL1SMN1; SMN2HDAC1
	SCHEMBL20558295	0.77	CYP4F2 (0.41)	ALDH1A1L3MBTL1SMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.