Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322881 | 0.90 | PRKCZ (0.42) | PRKCZCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18322951 | 0.88 | PRKCZ (0.42) | PRKCZCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18322938 | 0.86 | CHRNB1 (0.43) | PRKCZCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18322853 | 0.84 | HRH3 (0.43) | PRKCZAVPR2AVPR1ATTKCHEK1 | |
| SCHEMBL18322956 | 0.84 | PRMT5 (0.47) | PRKCZCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18318977 | 0.81 | PIK3CA (0.53) | AVPR2AVPR1APIK3CAMTORPIK3CD | |
| SCHEMBL18318408 | 0.81 | AVPR2 (0.47) | PRKCZAVPR2AVPR1APIK3CAHRH3 | |
| SCHEMBL18322902 | 0.80 | PDGFRB (0.47) | HRH3PDGFRBPDGFRA | |
| SCHEMBL18322866 | 0.80 | PDGFRB (0.47) | HRH3PDGFRBPDGFRA | |
| SCHEMBL18318841 | 0.79 | PIK3CA (0.49) | PRKCZAVPR2AVPR1APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310441-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Cephalon, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016205633-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-12-22 | — | — | WO | disclosed |