Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322904 | 0.82 | GSK3B (0.42) | GSK3BCARM1PRMT6FASNDRD2 | |
| SCHEMBL18322982 | 0.78 | GSK3B (0.43) | GSK3BFASNDRD2HTR7 | |
| SCHEMBL18318878 | 0.78 | GSK3B (0.49) | GSK3BFASNMAPK14 | |
| Hydrochloric Acid SCHEMBL18318321 | 0.77 | GSK3B (0.48) | GSK3BFASNMAPK14 | |
| SCHEMBL18331129 | 0.76 | GSK3B (0.47) | GSK3BFASNCHRNA7MAPK14 | |
| SCHEMBL4440481 | 0.75 | CARM1 (0.61) | CARM1PRMT6DRD4DRD2 | |
| SCHEMBL7501576 | 0.67 | KCNH2 (0.49) | DRD2HTR7 | |
| SCHEMBL18322946 | 0.67 | HTR7 (0.37) | GSK3BCARM1PRMT6HTR7 | |
| SCHEMBL3726615 | 0.66 | NPC1 (0.68) | GSK3B | |
| SCHEMBL29485612 | 0.66 | NPC1 (0.68) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310441-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Cephalon, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016205633-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-12-22 | — | — | WO | disclosed |