Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2347792 | 0.77 | HDAC4 (0.36) | SMN1; SMN2ALDH1A1MAPTBCHEP2RX1 | |
| Iodide SCHEMBL2347798 | 0.77 | HDAC4 (0.36) | SMN1; SMN2ALDH1A1MAPTBCHEP2RX1 | |
| SCHEMBL1918395 | 0.72 | ALDH1A1 (0.40) | CCR1SMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL28283765 | 0.69 | HDAC4 (0.43) | ALDH1A1MAPTBCHEP2RX1P2RX3 | |
| SCHEMBL11978688 | 0.66 | ELANE (0.50) | SMN1; SMN2CES2CES1ALDH1A1MAPT | |
| SCHEMBL1916632 | 0.66 | MAPT (0.46) | AKR1C3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20881602 | 0.65 | HTT (0.38) | SMN1; SMN2ALDH1A1MAPTLMNAMEN1 | |
| Toluene SCHEMBL48134 | 0.63 | LMNA (0.73) | SMN1; SMN2CES2CES1AKR1C3ALDH1A1 | |
| Toluene SCHEMBL2914390 | 0.63 | LMNA (0.73) | SMN1; SMN2CES2CES1AKR1C3ALDH1A1 | |
| Toluene SCHEMBL7355317 | 0.63 | LMNA (0.73) | SMN1; SMN2CES2CES1AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327735-B1 | METHOD FOR PREPARING POLYLACTIC ACID AND PRODUCTS THEREOF USING A TWIN-SCREW EXTRUDER | NANJING UNIV OF TECH (CN) | 2016-12-21 | — | — | EP | disclosed |