Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2347792 | 1.00 | HDAC4 (0.36) | HDAC4HDAC7HDAC5EGFRMTNR1A | |
| SCHEMBL29843820 | 0.98 | HDAC4 (0.37) | HDAC4HDAC7HDAC5EGFRMTNR1A | |
| Iodide SCHEMBL3822941 | 0.84 | STING1 (0.39) | POLBGAAALDH1A1MAPTNPSR1 | |
| SCHEMBL28283765 | 0.83 | HDAC4 (0.43) | HDAC4HDAC7HDAC5EGFRALDH1A1 | |
| SCHEMBL29843930 | 0.82 | STING1 (0.40) | POLBGAAALDH1A1MAPTNPSR1 | |
| SCHEMBL21990766 | 0.78 | MAPT (0.34) | POLBGAAMAPT | |
| SCHEMBL18324318 | 0.77 | CCR1 (0.46) | SMN1; SMN2ALDH1A1MAPTP2RX4P2RX1 | |
| SCHEMBL28003023 | 0.73 | HDAC4 (0.44) | HDAC4HDAC7HDAC5EGFRGAA | |
| SCHEMBL28979084 | 0.72 | CASP1 (0.37) | HDAC4HDAC7HDAC5EGFRMTNR1A | |
| SCHEMBL24398363 | 0.72 | GAA (0.44) | POLBGAASMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11404650-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-08-02 | — | — | US | disclosed |
| US-10381579-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-08-13 | — | — | US | disclosed |
| US-20150249225-A1 | STABILITY OLED MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-03 | — | — | US | disclosed |
| US-9051344-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| US-8007926-B2 | Luminescent compounds with carbene ligands | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-08-30 | — | — | US | disclosed |
| US-7902374-B2 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1878053-B1 | STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY | UNIVERSAL DISPLAY CORP (US) | 2009-08-26 | — | — | EP | disclosed |
| US-20090140640-A1 | LUMINESCENT COMPOUNDS WITH CARBENE LIGANDS | THOMPSON MARK E | 2009-06-04 | — | — | US | disclosed |
| US-7491823-B2 | Luminescent compounds with carbene ligands | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-02-17 | — | — | US | disclosed |
| US-7393599-B2 | Luminescent compounds with carbene ligands | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-07-01 | — | — | US | disclosed |
| WO-2008054584-A1 | IMPROVED STABILITY OLED MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| EP-1878053-A1 | STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY | Universal Display Corporation (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070088167-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2007-04-19 | — | — | US | disclosed |
| WO-2006121811-A1 | STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY | UNIVERSAL DISPLAY CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060251923-A1 | Stability OLED materials and devices | UNIVERSAL DISPLAY CORPORATION | 2006-11-09 | — | — | US | disclosed |
| US-20060024522-A1 | Luminescent compounds with carbene ligands | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2006-02-02 | — | — | US | disclosed |
| WO-2005113704-A2 | LUMINESCENT COMPOUNDS WITH CARBENE LIGANDS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050260441-A1 | Luminescent compounds with carbene ligands | UNIVERSITY OF SOUTHERN CALIFORNIA,THE | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11404650-B2 | Stability OLED materials and devices | OCIAD2, OCIAD1, OSBP2 | HDAC4 4624/4885HDAC7 4734/4885HDAC5 4837/4885 |
| US-10381579-B2 | Stability OLED materials and devices | OCIAD2, OCIAD1, OSBP2 | HDAC4 4613/4885HDAC7 4717/4885HDAC5 4834/4885 |
| US-20150249225-A1 | STABILITY OLED MATERIALS AND DEVICES | OCIAD2, OCIAD1, OSBP2 | HDAC4 4613/4885HDAC7 4717/4885HDAC5 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.